Neuroscience
The Department of Neuroscience at Barwon Health conducts research into the brain and the nervous system. Participating in large-scale global and national clinical trials as well as investigator initiated studies, we are held in high regard with our contribution to research into stroke, Multiple Sclerosis (MS), Motor Neurone Disease (MND), headaches and migraines, and autoimmune encephalitis.
Barwon Health is the primary centre for the national Motor Neurone Disease (MND) research database, which has patients registered from all over Australia from the 13 major MND clinics.
We are also involved in investigating new therapies for MS, which are evolving rapidly. Due to their complexity, these therapies require a high level of testing and oversight and the department has a dedicated MS Nurse who monitors patients receiving these and other experimental therapies.
Research Areas
Collaborating Organisations
| Calvary Health Care Bethlehem | Deakin University | |
| MND Australia | Monash University | |
| University of Sydney |
Research Team
- Professor Paul Talman, Consultant Neurologist
- A/P Ben Clissold, Consultant Neurologist
- Dr Cassie Nesbitt, Consultant Neurologist
- A/P Cameron Shaw, Consultant Neurologist
- Ms Katrina Sangster, Clinical Research Nurse
- Ms Michelle Hiddleston, Stroke Coordinator, Stroke Services
Research Grants
- MiNDAUS NHMRC partnership. Motor Neurone Disease: Patient centred care for a progressive neurological disease-evidence driving policy. Professor Paul Talman, 3 years
Featured Publications
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Vucic, S., Wray, N., Henders, A., Henderson, R., Talman, P., et al. (2022). MiNDAUS partnership: a roadmap for the management and cure of Motor Neurone Disease. Amyotrophic Lateral Sclerosis and frontotemporal degeneration. 23: 321-28 https://www.tandfonline.com/doi/epdf/10.1080/21678421.2021.1980889?needAccess=true |
| Bhattarai, A., Egan, G., Talman, P., et al. (2021). Magnetic resonance iron imaging in Amyotrophic Lateral Sclerosis. International Society for Magnetic Resonance in Medicine. 55 (5), 1283-1300. |
| Talman, P., Duong, T., Vucic, S., Mathers, S., et al. (2016). Identification and outcomes of clinical phenotypes in Amyotrophic Lateral Sclerosis/Motor Neuron Disease: Australian National Motor Neuron Disease observational chart. BMJ Open; 6. https://doi:10.1136/bmjopen-2016-012054 |
| Nesbitt, C., Rath, L., Yeh, W. Z., Zhong, M., Wesselingh, R., Monif, M., Richards, J., Minh, V. B., Jokubaitis, V. G., Skibina, O., Butzkueven, H., & van der Walt, A. (2020). MSCOVID19: Using social media to achieve rapid dissemination of health information. Multiple Sclerosis and Related Disorders, 45. https://doi.org/10.1016/j.msard.2020.102338 |
| Nesbitt C, Rath L, Zhong M, Cheng AC, Butzkueven H, Wesselingh R, Skibina O, Monif M, Yeh W, Brotherton JM, Reddel S, Van Der Walt A. (2021) Vaccinations in patients with multiple sclerosis: review and recommendations. Med J Aust. May; 214(8):350-354. https://doi:10.5694/mja2.51012 |
| Roos, I; Diouf, I; Sharmin, S; Horakova, D; Havrdova, EK; Patti, F; …. Shaw, C; et al. (2023). Comparative effectiveness in multiple sclerosis: A methodological comparison. Multiple Sclerosis Journal. Vol. 29, pp. 326-332 https://hdl.handle.net/10779/DRO/DU:22421632.v1 |
| Saul, AM; Taylor, BV; Blizzard, L; Simpson-Yap, S; Oddy, WH; Shivappa, N; … Shaw, C; et al. (2023). A pro-inflammatory diet in people with multiple sclerosis is associated with an increased rate of relapse and increased FLAIR lesion volume on MRI in early multiple sclerosis: A prospective cohort study. Multiple Sclerosis Journal, Vol. 29, pp. 1012-1023 https://hdl.handle.net/10779/DRO/DU:23621223.v1 |
| Cadilhac DA, Kim J, Tod EK, Morrison JL, Breen SJ, Jaques K, Grimley R, Jones B, Cloud GC, Kleinig T, Hillier S, Castley H, Lindley RI, Lannin NA, Middleton S, Yan B, Hill K, Clissold BB, Mitchell PJ, Anderson CS, Faux SG, Campbell BCV. (2021). AuSCR COVID-19 Reporting Consortium Group. COVID-19 Pandemic Impact on Care for Stroke in Australia: Emerging Evidence From the Australian Stroke Clinical Registry. Front Neurol. Feb 26; 12: 621495. https://doi:10.3389/fneur.2021.621495 |
| Lim, A., Singhal, S., Lavallee, P., Amarenco, P., Rothwell, PM., Albers, G., Sharma, M., Brown, R., Ranta, A., Maddula, M., Kleinig, T., Dawson, J., Elkind, M., Guarino, M., Coutts, S., Clissold, B., Ma, H., Phan, T. (2020). An International Report on the Adaptations of Rapid Transient Ischaemic Attack Pathways During the COVID-19 Pandemic. Journal of Stroke and Cerebrovascular Diseases. 29 (11) https://doi.org/10.1016/j.jstrokecerebrovasdis.2020.105228 |
Support Our Research
Participate in a clinical trial
To find out about clinical trials currently underway at Barwon Health, click here.
Donate
Clinical trials require ongoing investment and there are several ways to support this amazing work.
You can make a donation today and contribute to an item on our research wish list, consider a bequest in your will, or establish a lasting legacy fund in your name. No matter what size, your philanthropic support with deliver an immediate impact.
To donate now or for more information and further discuss your support, please contact the Barwon Health Foundation.
Wish List
To fund a 3 year Clinical Research Nurse position for clinical trials implementation in MND and stroke: >$20,000
Last Modified: Thursday, 02 November 2023
Research Lead
Professor Paul Talman BSc Hons MBBS FRACP PhD
Consultant Neurologist
Neuroscience Department
Kardinia House, Level 2, University Hospital Geelong
94215 0710