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Barwon Health / Research

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Be part of a study examining whether different dairy can influence our mood

Tuesday, 25 May 2021

A world-first food trial looking at how different types of dairy might affect our mental, brain and gut health needs more volunteers!

The 'Moo'D Study', led by the IMPACT Food and Mood Centre, is comparing a group of women who consume conventional dairy products compared with those whose diet includes only dairy free from the A1-protein.

Director of the Food and Mood Centre Professor Felice Jacka said the team was currently recruiting women with 'low mood', aged between 18 and 75, to take part in the trial which was interrupted last year by the pandemic. "We know that good nutrition is important for mental and brain health as well as physical health, but there are still unanswered questions about what particular foods within our diet might be important,” Professor Jacka said. "Dairy products, such as milk, yoghurt and cheese, are a major component of the Australian diet, and there a range of products on the market from low-fat to full-fat, and A1-protein free. But it's not clear how these products might influence our mental, brain, and gut health."

Professor Jacka said casein was the predominant protein found in milk products, with A1 and A2 beta-casein two of the more common types. "To date, research has told us that these milk proteins differ in their structure and produce two different metabolic end- products upon digestion," she said. "There is some limited evidence that by-products from the digestion of certain milk proteins may influence our health, including our gut health, however far more research in humans is needed. "For this reason, we are interested in comparing the possible effects of A2-only milk and conventional milk products (containing both the A1 and A2 protein) on psychological distress in women. "We're also interested in comparing the possible differences between these two dairy products on gut symptoms, the gut microbiota, cognition, body composition, sleep patterns, quality of life and a range of other health parameters."

The 16-week double-blind, randomised controlled trial is being carried out at University Hospital Geelong. Participants are provided with dairy products for the duration of the trial and complete a range of assessments in clinic and at home. While the trial began in 2019, the disruptions of last year mean the study team is still looking for participants to take part in the trial before recruitment closes on 2 July 2021.

For more information on the Moo'D study, visit www.foodandmoodcentre.com.au/themoodstudy. This study has been funded with a donation from the a2 Milk Company but will be carried out independently by the Food and Mood Centre research team.